Time course of nigrostriatal degeneration in parkinson's disease
Identifieur interne : 000804 ( Main/Corpus ); précédent : 000803; suivant : 000805Time course of nigrostriatal degeneration in parkinson's disease
Auteurs : P. Riederer ; St. WuketichSource :
- Journal of Neural Transmission [ 0300-9564 ] ; 1976-09-01.
Abstract
Summary: It could be shown that the post mortem analysis of biogenic amines, precursors, and metabolites in the human brain are influenced by various parameters. 1. The patient's medical history; long term observation of the course of the disease; age; sex. 2. Terminal illness; duration of terminal illness. 3. Previous treatment with drugs; last drugs. 4. Time interval between last drug treatment and death; time of day and date of last drug consumption. 5. Rapidity of death; time of death; duration of coma. 6. Changes occurring in tissues before death; patient's constitution during terminal illness. 7. Changes in concentration of the biogenic amines, precursors, and metabolites depending on the patient's age. 8. Time between death and necropsy. 9. Dissection of specimen. 10. Period of storage; temperature of storage. 11. Chronobiological rhythm of substances. 12. Methods of assay. 13. Homogeneity of all mentioned parameters in the control group and patient group. For the first time it could be demonstrated that the time course of nigrostriatal degeneration, independent of the age of the parkinsonian at the beginning of the illness, is linear for the last stage and the denervation progressively increases as the duration of illness progresses.
Url:
DOI: 10.1007/BF01249445
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ISTEX:A35592D7C0994DA57D1549413F928CE4889D684FLe document en format XML
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Riederer</name><affiliation><mods:affiliation>Ludwig Boltzmann Neurochemistry Institute, Geriatric Hospital of the City of Vienna-Lainz, Austria</mods:affiliation></affiliation><affiliation><mods:affiliation>The Pathological Institute of the Hospital of the City of Vienna-Lainz, Austria</mods:affiliation></affiliation></author><author><name sortKey="Wuketich, St" sort="Wuketich, St" uniqKey="Wuketich S" first="St." last="Wuketich">St. Wuketich</name><affiliation><mods:affiliation>Ludwig Boltzmann Neurochemistry Institute, Geriatric Hospital of the City of Vienna-Lainz, Austria</mods:affiliation></affiliation><affiliation><mods:affiliation>The Pathological Institute of the Hospital of the City of Vienna-Lainz, Austria</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:A35592D7C0994DA57D1549413F928CE4889D684F</idno><date when="1976" year="1976">1976</date><idno type="doi">10.1007/BF01249445</idno><idno type="url">https://api.istex.fr/document/A35592D7C0994DA57D1549413F928CE4889D684F/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">000804</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Time course of nigrostriatal degeneration in parkinson's disease</title><author><name sortKey="Riederer, P" sort="Riederer, P" uniqKey="Riederer P" first="P." last="Riederer">P. Riederer</name><affiliation><mods:affiliation>Ludwig Boltzmann Neurochemistry Institute, Geriatric Hospital of the City of Vienna-Lainz, Austria</mods:affiliation></affiliation><affiliation><mods:affiliation>The Pathological Institute of the Hospital of the City of Vienna-Lainz, Austria</mods:affiliation></affiliation></author><author><name sortKey="Wuketich, St" sort="Wuketich, St" uniqKey="Wuketich S" first="St." last="Wuketich">St. Wuketich</name><affiliation><mods:affiliation>Ludwig Boltzmann Neurochemistry Institute, Geriatric Hospital of the City of Vienna-Lainz, Austria</mods:affiliation></affiliation><affiliation><mods:affiliation>The Pathological Institute of the Hospital of the City of Vienna-Lainz, Austria</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Neural Transmission</title><title level="j" type="sub">Basic neurosciences and genetics, Parkinson's disease and allied conditions, Alzheimer's disease and related disorders, biological psychiatry</title><title level="j" type="abbrev">J. 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The patient's medical history; long term observation of the course of the disease; age; sex. 2. Terminal illness; duration of terminal illness. 3. Previous treatment with drugs; last drugs. 4. Time interval between last drug treatment and death; time of day and date of last drug consumption. 5. Rapidity of death; time of death; duration of coma. 6. Changes occurring in tissues before death; patient's constitution during terminal illness. 7. Changes in concentration of the biogenic amines, precursors, and metabolites depending on the patient's age. 8. Time between death and necropsy. 9. Dissection of specimen. 10. Period of storage; temperature of storage. 11. Chronobiological rhythm of substances. 12. Methods of assay. 13. Homogeneity of all mentioned parameters in the control group and patient group. For the first time it could be demonstrated that the time course of nigrostriatal degeneration, independent of the age of the parkinsonian at the beginning of the illness, is linear for the last stage and the denervation progressively increases as the duration of illness progresses.</div></front></TEI><istex><corpusName>springer</corpusName><author><json:item><name>P. 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The patient's medical history; long term observation of the course of the disease; age; sex. 2. Terminal illness; duration of terminal illness. 3. Previous treatment with drugs; last drugs. 4. Time interval between last drug treatment and death; time of day and date of last drug consumption. 5. Rapidity of death; time of death; duration of coma. 6. Changes occurring in tissues before death; patient's constitution during terminal illness. 7. Changes in concentration of the biogenic amines, precursors, and metabolites depending on the patient's age. 8. Time between death and necropsy. 9. Dissection of specimen. 10. Period of storage; temperature of storage. 11. Chronobiological rhythm of substances. 12. Methods of assay. 13. Homogeneity of all mentioned parameters in the control group and patient group. For the first time it could be demonstrated that the time course of nigrostriatal degeneration, independent of the age of the parkinsonian at the beginning of the illness, is linear for the last stage and the denervation progressively increases as the duration of illness progresses.</abstract><qualityIndicators><score>7.34</score><pdfVersion>1.3</pdfVersion><pdfPageSize>432 x 648 pts</pdfPageSize><refBibsNative>false</refBibsNative><keywordCount>0</keywordCount><abstractCharCount>1261</abstractCharCount><pdfWordCount>6016</pdfWordCount><pdfCharCount>38304</pdfCharCount><pdfPageCount>25</pdfPageCount><abstractWordCount>195</abstractWordCount></qualityIndicators><title>Time course of nigrostriatal degeneration in parkinson's disease</title><genre><json:string>research-article</json:string></genre><host><volume>38</volume><pages><last>301</last><first>277</first></pages><issn><json:string>0300-9564</json:string></issn><issue>3-4</issue><subject><json:item><value>Pharmacology/Toxicology</value></json:item><json:item><value>Neurology</value></json:item><json:item><value>Psychiatry</value></json:item></subject><journalId><json:string>702</json:string></journalId><genre><json:string>Journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1435-1463</json:string></eissn><title>Journal of Neural Transmission</title><publicationDate>1976</publicationDate><copyrightDate>1976</copyrightDate></host><publicationDate>1976</publicationDate><copyrightDate>1976</copyrightDate><doi><json:string>10.1007/BF01249445</json:string></doi><id>A35592D7C0994DA57D1549413F928CE4889D684F</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/A35592D7C0994DA57D1549413F928CE4889D684F/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/A35592D7C0994DA57D1549413F928CE4889D684F/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/A35592D7C0994DA57D1549413F928CE4889D684F/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Time course of nigrostriatal degeneration in parkinson's disease</title><title level="a" type="sub" xml:lang="en">A detailed study of influential factors in human brain amine analysis</title><respStmt xml:id="ISTEX-API" resp="Références bibliographiques récupérées via GROBID" name="ISTEX-API (INIST-CNRS)"></respStmt></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Springer-Verlag</publisher><pubPlace>Vienna</pubPlace><availability><p>SPRINGER</p></availability><date>1976-02-27</date></publicationStmt><notesStmt><note>Dedicated to Professor W. 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For the first time it could be demonstrated that the time course of nigrostriatal degeneration, independent of the age of the parkinsonian at the beginning of the illness, is linear for the last stage and the denervation progressively increases as the duration of illness progresses.</p></abstract><textClass><keywords scheme="Journal Subject"><list><head>Medicine & Public Health</head><item><term>Pharmacology/Toxicology</term></item><item><term>Neurology</term></item><item><term>Psychiatry</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1976-02-27">Created</change><change when="1976-09-01">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2016-3-2">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/A35592D7C0994DA57D1549413F928CE4889D684F/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Springer, Publisher found" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//Springer-Verlag//DTD A++ V2.4//EN" URI="http://devel.springer.de/A++/V2.4/DTD/A++V2.4.dtd" name="istex:docType"></istex:docType><istex:document><Publisher><PublisherInfo><PublisherName>Springer-Verlag</PublisherName><PublisherLocation>Vienna</PublisherLocation></PublisherInfo><Journal><JournalInfo JournalProductType="ArchiveJournal" NumberingStyle="Unnumbered"><JournalID>702</JournalID><JournalPrintISSN>0300-9564</JournalPrintISSN><JournalElectronicISSN>1435-1463</JournalElectronicISSN><JournalTitle>Journal of Neural Transmission</JournalTitle><JournalSubTitle>Basic neurosciences and genetics, Parkinson's disease and allied conditions, Alzheimer's disease and related disorders, biological psychiatry</JournalSubTitle><JournalAbbreviatedTitle>J. 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long term observation of the course of the disease; age; sex.</Para></ItemContent></ListItem><ListItem><ItemNumber>2.</ItemNumber><ItemContent><Para>Terminal illness; duration of terminal illness.</Para></ItemContent></ListItem><ListItem><ItemNumber>3.</ItemNumber><ItemContent><Para>Previous treatment with drugs; last drugs.</Para></ItemContent></ListItem><ListItem><ItemNumber>4.</ItemNumber><ItemContent><Para>Time interval between last drug treatment and death; time of day and date of last drug consumption.</Para></ItemContent></ListItem><ListItem><ItemNumber>5.</ItemNumber><ItemContent><Para>Rapidity of death; time of death; duration of coma.</Para></ItemContent></ListItem><ListItem><ItemNumber>6.</ItemNumber><ItemContent><Para>Changes occurring in tissues before death; patient's constitution during terminal illness.</Para></ItemContent></ListItem><ListItem><ItemNumber>7.</ItemNumber><ItemContent><Para>Changes in concentration of the biogenic amines, precursors, and metabolites depending on the patient's age.</Para></ItemContent></ListItem><ListItem><ItemNumber>8.</ItemNumber><ItemContent><Para>Time between death and necropsy.</Para></ItemContent></ListItem><ListItem><ItemNumber>9.</ItemNumber><ItemContent><Para>Dissection of specimen.</Para></ItemContent></ListItem><ListItem><ItemNumber>10.</ItemNumber><ItemContent><Para>Period of storage; temperature of storage.</Para></ItemContent></ListItem><ListItem><ItemNumber>11.</ItemNumber><ItemContent><Para>Chronobiological rhythm of substances.</Para></ItemContent></ListItem><ListItem><ItemNumber>12.</ItemNumber><ItemContent><Para>Methods of assay.</Para></ItemContent></ListItem><ListItem><ItemNumber>13.</ItemNumber><ItemContent><Para>Homogeneity of all mentioned parameters in the control group and patient group.</Para></ItemContent></ListItem></OrderedList></Para><Para>For the first time it could be demonstrated that the time course of nigrostriatal degeneration, independent of the age of the parkinsonian at the beginning of the illness, is linear for the last stage and the denervation progressively increases as the duration of illness progresses.</Para></Abstract><ArticleNote Type="Dedication"><SimplePara>Dedicated to Professor<Emphasis Type="Italic">W. Birkmayer</Emphasis>, M.D., on the occasion of his 65th birthday.</SimplePara></ArticleNote></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Time course of nigrostriatal degeneration in parkinson's disease</title><subTitle>A detailed study of influential factors in human brain amine analysis</subTitle></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Time course of nigrostriatal degeneration in parkinson's disease</title><subTitle>A detailed study of influential factors in human brain amine analysis</subTitle></titleInfo><name type="personal"><namePart type="given">P.</namePart><namePart type="family">Riederer</namePart><affiliation>Ludwig Boltzmann Neurochemistry Institute, Geriatric Hospital of the City of Vienna-Lainz, Austria</affiliation><affiliation>The Pathological Institute of the Hospital of the City of Vienna-Lainz, Austria</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">St.</namePart><namePart type="family">Wuketich</namePart><affiliation>Ludwig Boltzmann Neurochemistry Institute, Geriatric Hospital of the City of Vienna-Lainz, Austria</affiliation><affiliation>The Pathological Institute of the Hospital of the City of Vienna-Lainz, Austria</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="OriginalPaper"></genre><originInfo><publisher>Springer-Verlag</publisher><place><placeTerm type="text">Vienna</placeTerm></place><dateCreated encoding="w3cdtf">1976-02-27</dateCreated><dateIssued encoding="w3cdtf">1976-09-01</dateIssued><copyrightDate encoding="w3cdtf">1976</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Summary: It could be shown that the post mortem analysis of biogenic amines, precursors, and metabolites in the human brain are influenced by various parameters. 1. The patient's medical history; long term observation of the course of the disease; age; sex. 2. Terminal illness; duration of terminal illness. 3. Previous treatment with drugs; last drugs. 4. Time interval between last drug treatment and death; time of day and date of last drug consumption. 5. Rapidity of death; time of death; duration of coma. 6. Changes occurring in tissues before death; patient's constitution during terminal illness. 7. Changes in concentration of the biogenic amines, precursors, and metabolites depending on the patient's age. 8. Time between death and necropsy. 9. Dissection of specimen. 10. Period of storage; temperature of storage. 11. Chronobiological rhythm of substances. 12. Methods of assay. 13. Homogeneity of all mentioned parameters in the control group and patient group. 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